The splice acceptor site and the first 57 nucleotides of exon 2 were replaced with the neomycin-resistance gene. The disrupted portion of exon 2 encodes amino acids 47 to 66, which encompasses the binding site for EIF4E. (J:72217)
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The splice acceptor site and the first 57 nucleotides of exon 2 were replaced with the neomycin-resistance gene. The disrupted portion of exon 2 encodes amino acids 47 to 66, which encompasses the binding site for EIF4E. (J:72217)