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A neomycin selection cassette replaced 200 bp of the first exon, containing sequences encoding the signal peptide. Northern blot analysis on RNA derived from testis and cerebrum of homozygous mice confirmed that no detectable transcript was produced from this allele. Western blot analysis on extracts derived form testis and uterus of homozygous mice confirmed that no detectable protein is expressed from this allele. (J:46376)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
