A knock-in cassette containing a loxP-flanked neomycin gene followed by a human DDIT3 gene replaced exons 8 and 9. This allele expresses a fusion protein of FUS and Neo in which the neomycin sequences replace the RNA-binding C-terminal portion of the gene; the inserted DDIT3 gene is not expressed. (J:75732)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count