An insertion vector that contained a mutated exon 3 and a neomycin selection cassette was inserted into intron 2 of the gene. The mutated exon 3 contained an oligonucleotide that introduced stop codons in all three reading frames. (J:15244)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count