LoxP sites were inserted into intronic sequences flanking three exons. An adjacent loxP flanked neomycin selection cassette was removed in ES cells by transient Cre recombinase transfection prior to the production of chimeric mice. (J:75421)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count