This allele is a derivative of Nf1tm1Par. Exons 31 and 32 were deleted via Cre mediated recombination. This was achieved by mating mice carrying the NF1tm1Par mutation to mice carrying Egr2tm2(Cre)Pch (strain 129S2/SvPas). This deletion is heritable, and is transmitted through the germ line. (J:68558)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Intragenic deletion
--
1
24
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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