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A termination codon, a GFP gene and a loxP flanked neomycin selection cassette were inserted into exon 5. Immunoblot analysis showed that homozygous mouse tissues were entirely negative for the encoded protein, and immunohistochemical detection in kidney sections of homozygous mice showed absence of the protein. (J:61946)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
