This transgene expresses a bicistronic mRNA containing Cre recombinase sequences and an IRES-human placental alkaline phosphatase under the control of the mouse Hoxa1 enhancer III and a basal TATA box promoter. This enhancer/promoter is active in embryonic floorplate, notochord and gut epithelium beginning at E8.5 through E14.5. (J:67902)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count