This transgene expresses Cre recombinase under the control of a human beta-actin promoter, which is active in all embryonic cells at or before the blastocyst stage. Line number 2 contains a single copy of the transgene inserted into intron 4 of Tmem163 (chr1:129,442,346; NCBI37/mm9) with three intronic deletions of 2.2, 7.3 and 3.2 kb, respectively, surrounding the transgene integration site. (J:46833, J:240920)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
FVB/N
--
Insertion, Intragenic deletion
--
1
1
378

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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