This allele is a derivative of Wasltm1Wehl. Cre-mediated recombination in vivo removed exons 6-9 in the germline, eliminating the effector domains and leaving a single loxP site in place of the deleted sequence. The authors predict that splicing exon 5 to the remaining exon 10 would create a premature stop codon. (J:73609)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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