This allele is a derivative of Wasltm1Wehl. Cre-mediated recombination in vivo removed exons 6-9 in the germline, eliminating the effector domains and leaving a single loxP site in place of the deleted sequence. The authors predict that splicing exon 5 to the remaining exon 10 would create a premature stop codon. (J:73609)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count