A neomycin selection cassette replaced the sequences encoding the bHLH domain. In addition, a lacZ gene was inserted in frame into the beginning of the coding sequences. A beta-galactosidase fusion protein was expressed from this allele under the control of the endogenous promoter. RT-PCR analysis confirmed that no transcript containing Atoh7 coding sequences is produced from this allele. (J:70746)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion, Intragenic deletion
--
1
4
25

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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