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This allele is a derivative of Nodaltm1Mku. Cre mediated recombination was achieved by crossing Nodaltm1Mku mice with transgenic mice expressing Cre under the control of the EIIa promoter. The recombination effectively removed the IRES beta-geo cassette, part of the 1st intron, the 2nd and 3rd exons, the 2nd intron and the 3'UTR of the Nodal gene. (J:73506)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
