A genomic fragment containing sequences encoding the first zinc finger motif was replaced with a neomycin selection cassette. This region encodes an essential portion of the protein common to all encoded isoforms. Northern blot analysis on RNA derived from E13.5 homozygous embryos demonstrated that no detectable transcript is produced from this allele. (J:29061)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion, Intragenic deletion
--
1
5
12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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