This allele is a derivative of Blmtm2Brd. Three copies of a targeting vector that contained loxP sites inserted into the gene. Cre mediated recombination led to a deletion of the copies. This allele retains an extra copy of exon 3. However, western blot analysis on protein extracts of testes demonstrated that no detectable protein was produced from this allele. (J:66261)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
Insertion
--
1
3
17

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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