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A genomic fragment containing the first coding exon was replaced with a neomycin selection cassette. RT-PCR analysis on total embryo RNA from homozygous embryos demonstrated that an aberrant transcript is produced from this allele, but the authors predict that no functional protein can be produced. (J:59282)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
