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EN
Homologous recombination introduced a floxed neomycin resistance cassette into intron 2, and a single loxP site into intron 1. Cre-mediated recombination in vivo under the control of a CMV promoter excised the neo cassette in the germline, leaving single loxP sites flanking exon 2, which encodes roughly a third of the extracellular domain of the receptor within the ligand-binding domain. (J:75074, J:97780)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
