A neomycin selection cassette was inserted into exon 2, into sequences encoding the amino terminal V-like domain. Northern blot analysis demonstrated that no stable transcript was produced from this allele. Immunocytochemistry analysis demonstrated that no functional protein was present on the surface of lymphocytes. (J:3149)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count