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PCR analysis on genomic DNA derived from mice carrying the In(3)55K inversion suggests that a disruption 3' to base 844 of exon 7 results in the mutation. Northern blot analysis on mRNA derived from liver RNA of homozygous mice confirmed that negligible amounts of encoded transcript was produced from this allele. (J:70677)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
