A lacZ-PGK-neomycin resistance cassette replaced part of exon 3, all of exon 4, and part of exon 5, including sequences encoding the amino terminus of the mature protein. Northern blot analysis of activated peritoneal macrophages did not detect transcript in homozygous mutant mice. (J:47429, J:92002)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count