Stop codons are inserted into all three reading frames of the signal sequence followed by a frameshift and the insertion, after CR1, of IRES-lacZ and PGK-neo cassettes to further disrupt the gene. Gene transcripts were undetectable in "node stage" embryos. (J:60303, J:83662)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count