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An Emx2 cDNA was inserted into the Otx2 gene as follows: the Emx2 cDNA was inserted at the start codon of the Otx2 gene followed by a loxP-flanked neomycin selection cassette. Resulting chimeric mice were bred to females expressing Cre in resulting zygotes, and the F1 generation was screened for the removal of the neomycin selection cassette. (J:70745)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
