This allele confers lung tumor susceptibility compared to BALB/cJ. This allele differs from wild-type in the presence of Cys at amino acid residue 968 rather than Arg as in wild-type. The allele is present in the SWR/J and in SWR/Bm and is absent in all 77 other strains tested including BALB/c.
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count