LoxP sites were inserted flanking exon 11 by homologous recombination. Subsequent Cre-mediated recombination in ES cells excised an adjacent PGK-neomycin and thymidine kinase cassette prior to the production of chimeric mice. (J:73028)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count