Gene trap vector pGT1.8TM was inserted into the gene. The fusion protein conatins the first 1091 amino acids of the locus, including the entire short arm and the first 63 amino acids of its helical domain II followed by the transmembrane domain and Betageo from the vector. Betagal expression was detected in neurons of many regions, including the cerebral cortex and hippocampal formation. (J:85792)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
Recessive
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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