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These transgenic mice express the tetracycline-inhibitable transcription factor (tTA) under the control of liver-specific mouse albumin promoter. Constitutive expression of tTA in liver makes this strain suitable for use in creating bitransgenic mice that can, by withdrawing tetracycline, inducibly express a gene of interest in the liver, when the gene of interest is under the direction of the tetracycline responsive promoter, TetOp (J:69003)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
