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EN
A single polymorphism (G to A) results in the amino acid aspartic acid at position 293 in strains C3H/HeJ, DBA/2J, NZW/LacJ, P/J and SJL. By comparison strains 129/Sv, A/J, AKR/J, B10.S/DvTe, BALB/cJ, BALB/cByJ, C57BL/6J, CBA/J, DBA/1J, FVB/NJ, NOD/LtJ, NZB/BInJ and PL/J contain a glycine at position 293. This allele confers susceptibility to EAE comapred with B10.S/DvTe. (J:204384)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
