Log In|Sign Up
EN
The presence of AKR/J, Cast/Ei, or 129P2/OlaHsd alleles protect tubby mice from hearing loss, while the C57BL/6 allele renders tubby mice susceptible to hearing loss. Numerous sequence polymorphisms in Mtap1a were observed between the susceptible and resistant strains. Verification of Mtap1a as the gene responsible for the moth1 phenotype was achieved by transgenic rescue. (J:75815)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
