A neomycin resistance cassette replaced exons E2 through T, which encode most of the receptor. In situ hybridization using a probe transcribed from rat receptor cDNA detected strong signal in four, and no signal in one, of five E9.5 embryos from heterozygous matings. (J:34604)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count