A cassette containing nls-lacZ and neo was inserted at the start codon, resulting in the deletion of sequence encoding 108 residues comprising the entire dimerization domain and a portion of the B domain, as well as the majority of intron 1. Expression of beta-galactosidase was observed via Xgal staining. (J:31627)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion, Intragenic deletion
--
1
13
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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