A neomycin resistance cassette was inserted into the exon that encodes the homeobox sequences of the protein. A mutant transcript consisting of neomycin sequences fused to 3' gene sequences was produced, but stop codons in the neomycin gene are predicted to prevent expression of protien from this allele. (J:73592)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count