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A neomycin selection cassette replaced a genomic fragemnt that contained two exons that encode the first P-loop. RT-PCR analysis on RNA derived from brain of homozygous mice demonstrated that an aberrant transcript was made that spliced around the missing exons to generate an mRNA that maintained an in-frame deletion. (J:44522)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
