A neomycin resistance cassette replaced exon 2, deleting sequences that encode the homeodomain, the splice acceptor site, and flanking intron sequences. Whole-mount immunohistochemical studies did not detect protein in homozygous mutant embryos. (J:20779)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count