A transgene containing a mutant form of human TGFB1 expressed under the control of a mouse alpha-cardiac myosin heavy chain promoter inserted into an unidentified locus in this line. Other transgenic lines generated using this construct did not correlate with the associated mutant phenotype of mice bearing the transgene in this line, suggesting that the transgene insertion was a mutational event. (J:59903)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C3HeB/FeJ
--
Insertion
Dominant
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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