An in frame lacZ-loxP-PGK-TKNEOpA-loxP cassette 28bp upstream of the homeobox in exon 2 replaced sequences encoding the conserved protein domains. Analysis of beta-galactosidase expression in heterozygous embryos of E9.5 to E12.5 showed essentially no differences with endogenous Alx3 expression. (J:71880)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intragenic deletion
--
1
1
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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