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A construct consisting of a human beta-actin promoter driving expression of a rat lectin cDNA was injected into fertilized eggs. The construct integrated in multiple tandem copies into the coding region of the Pcdh15 gene, disupting the coding seqence for the fourth cdh domain. Truncated transcripts are produced from this allele that are smaller than normal size due to the SV40 poly(A) site that is present in the transgene. (J:66738)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
