A PGK-hygromycin resistance cassette replaced exon 1 of the wild-type Scx allele in heterozygous ES cells (Gt(ROSA)26Sor+/- Scxtm1Eno-+/-). Injection of lacZ-marked Scxtm1Eno/Scxtm2Eno ES cells into wild-type blastocysts resulted in chimeric embryos. (J:55991)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd and C57BL/6 and Swiss
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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