Insertion of a neomycin resistance cassette into exon 2 disrupted sequences that encode the DNA binding homeodomain. Northern analysis using an exon 2 probe detected novel transcripts and no wild-type transcripts in lung and kidney of homozygous mutant mice. (J:71563)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count