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A PGK-neomycin resistance cassette replaced 1.4kb of sequence including the exon that encodes amino acids 29-50, and introduced a frame shift downstream of the insertion. In an immune-complex in vitro tyrosine kinase assay, antiserum raised against the C-terminal of the protein did not detect wild-type protein in lysates of homozygous mutant E10.5 embryos. (J:34200)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
