A cre gene was inserted in frame into the gene immediately following the endogenous start codon. An frt-flanked neomycin selection cassette that was inserted following the cre gene was removed by Flp-mediated recombination in ES cells prior to production of chimeric mice. This promoter is active after birth in the epidermis and hair follicles as well as the eye, tongue, and esophagus. (J:69463)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion
--
1
12
16

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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