Insertion of a neomycin resistance cassette into the FspI site of exon 2, located immediately before the sequence encoding the first transmembrane domain. Northern blots of renal tissue did not detect Ptger1 transcript in homozygous mutant mice. (J:70534)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count