A lacZ gene followed by a neomycin selection cassette replaced a 263 bp DNA fragment containing the endogenous translation start site. A beta-galactosidase protein is expressed from this allele under the control of the endogenous promoter, but the expression pattern does not faithfully reflect the expression pattern of the endogenous gene. (J:50004)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv-Gpi1c
Targeted
Insertion, Intragenic deletion
--
1
2
31

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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