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A PGK-neomycin resistance cassette replaced 54 bp of the 5' part of exon 3 and parts of the second intron. The mutated allele contains a rearrangement downstream from the insertion site with a partial duplication of exon 3 sequences. Northern blot analysis of brain and testis detected nearly no encoded mRNA in homozygous mice. (J:35826)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
