This cytogenetic transposition comprises a duplication of a Y Chromosome short arm segment, originally from the RIII inbred strain, that was transferred to the distal end of the long arm adjacent to the pseudoautosomal region which normally recombines with the X Chromosome during meiosis. During meiosis the duplicated region from the Y translocates to the X Chromosome of one-half of the X-bearing gametes. Genetic females with a male phenotype result when these gametes fertilize X bearing eggs. At least five loci map to the Tp(Y)1Ct segment: Hya, Spy, Tdy(Sry), Zfy1, and Zfy2. (J:6907, J:9332, J:193163)
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基础信息

模型ID
品系来源
等位基因类型
突变
遗传方式
基因表达
相关疾病
参考文献
RIII
Spontaneous
Translocation
Dominant
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表型特征

标签摘要:
hm: 纯合子
ht: 杂合子
cn: 条件基因型
cx: 复合型:涉及多基因组
tg: 转基因
ot: 其他:半合子、不确定...
(F): 雌性
(M): 雄性
观察到的表型
N: 正常表型
(#): 上标括号内为相关疾病数量
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