This cytogenetic transposition comprises a duplication of a Y Chromosome short arm segment, originally from the RIII inbred strain, that was transferred to the distal end of the long arm adjacent to the pseudoautosomal region which normally recombines with the X Chromosome during meiosis. During meiosis the duplicated region from the Y translocates to the X Chromosome of one-half of the X-bearing gametes. Genetic females with a male phenotype result when these gametes fertilize X bearing eggs. At least five loci map to the Tp(Y)1Ct segment: Hya, Spy, Tdy(Sry), Zfy1, and Zfy2. (J:6907, J:9332, J:193163)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
RIII
Spontaneous
Translocation
Dominant
--
--
33

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top