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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
Amyotrophic Lateral Sclerosis 1
USH2A c.8559-2A>G
Cystic Fibrosis
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Gene editing
Otx1
tm1Asim
Alias:
Otx1
-
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Basic Information
Phenotypes
References Literature
A 2.3kb fragment, including the coding regions of exons 1 and 2, was replaced by a LacZ gene. J:135697 (PMID:18294714) states that mice homozygous for this allele are not "Otx1-complete null" mice, but no details are given. (J:35640)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2136272
129P2/OlaHsd-Hprt1b-m3
Targeted
Insertion, Intragenic deletion
Recessive
1
--
17
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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