A point mutation was introduced that altered codon 369 from one encoding glycine to one encoding cysteine (G369C). A loxP flanked neomycin cassette inserted into an adjacent intron was removed via Cre mediated recombination in this derivative of Fgfr3tm3Cxd. (J:69849)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count