A Pdgfa cDNA was inserted between a SacI site and a KpnI site in the 5'UTR of the Myf5 gene. An adjacent loxP-flanked neomycin cassette was retained in this allele. Alteration in the expression pattern of Pdgfa was noted in homozygous mutant embryos as assayed by in situ hybridization. (J:65301)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJaeSor
Targeted
Insertion
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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