A cDNA encoding PDGFbetaR was targeted into the Pdgfrb locus. This allele serves as a control for Pdgfrbtm5Sor. The cDNA was inserted in frame into a Sma1 site in the second coding exon. Western blot analysis indicated that expression of the targeted Pdgfr locus was disrupted and the introduced receptor was expressed. (J:67735)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count