A PGK-neomycin resistance cassette replaced part of the first and all of the second exon encoding short consensus repeat (SCR) 14. Flow cytometry of spleen cells using three different rat antimouse CR2 monoclonal antibodies showed that homozygous mutant mice were deficient in the expression of the receptors. (J:35112)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1+
Targeted
Insertion, Intragenic deletion
--
1
5
44

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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