LoxP sites were inserted into the gene that flanked exons 5 and 6. An frt-flanked neomycin selection cassette was also inserted in an adjacent intron, but had no effect on the normal expression of the gene. (J:62712)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count