A lacZ-neomycin resistance cassette was inserted in-frame into exon 3b and placed lacZ under control of the endogenous promoter. RT-PCR studies of homozygous E10.5 embryos showed that trancripts lacking the sequences encoding the functional domains were produced from this allele. (J:29958)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count